Cardiac glycosides and COVID-19: would it be a promising therapeutic approach?

Antioxidant Supplements: A Promising Approach to improving COVID-19 Demonstrations

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) that causes COVID-19 could progress to acute respiratory distress syndrome (ARDS). The immune cells' migration in response to virus lead to cell death by releasing oxidizing free radicals. These oxidizing free radicals mediate NF-κB activation and induce transcription of cytokine-producing genes that eventually a cytokine storm ensues...

IJEE Soapbox: A World free of pArAsites And vectors: Would it be heAven, or Would it be hell?

This is of course impossible, but Gould’s thought experiment is a useful conceptual exercise which brings out key issues of determinism versus randomness in history. More broadly, it can be illuminating to ponder all kinds of implausible and radical scenarios, in effect bracketing the real world with visions of possible worlds. What would our world now be like if, at some time in the past, a ma...

The COVID-19 Pandemic: Is It A Wolf Consuming Fertility?

Cardiac glycosides as novel cancer therapeutic agents.

The class of steroid-like compounds designated cardiac glycosides includes well-known drugs such as digoxin, digitoxin, and ouabain. Their continued efficacy in treatment of congestive heart failure and as anti-arrhythmic agents is well appreciated. Less well known, however, is the emerging role of this category of compounds in the prevention and/or treatment of proliferative diseases such as c...

Therapeutic potential of Paclitaxel against COVID-19

The coronavirus disease-2019(COVID-19) was reported in Wuhan, China, in late December 2019 and soon became the most serious global health challenge due to high rate of human-to-human transmission. The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), is a single-stranded RNA virus and belongs to the large Coronaviridae family. Paclitaxel, an antineoplastic drug extracted from the Tax...